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Index > Protein center > Thbd(Gene name) > Mouse
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  • Thbd (Gene name),
  • Thrombomodulin (Protein name ),  TRBM_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Thbd;
    Protein name:
    Thrombomodulin(TM);
    Alternative:
    Fetomodulin;
    CD:
    CD141;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    577
    Sequence:
    50:
    MLGIFFLGVL | APASLGLSAL | AKLQPTGSQC | VEHECFALFQ | GPATFLDASQ | 
    100:
    ACQRLQGHLM | TVRSSVAADV | ISLLLSQSSM | DLGPWIGLQL | PQGCDDPVHL | 
    150:
    GPLRGFQWVT | GDNHTSYSRW | ARPNDQTAPL | CGPLCVTVST | ATEAAPGEPA | 
    200:
    WEEKPCETET | QGFLCEFYFT | ASCRPLTVNT | RDPEAAHISS | TYNTPFGVSG | 
    250:
    ADFQTLPVGS | SAAVEPLGLE | LVCRAPPGTS | EGHWAWEATG | AWNCSVENGG | 
    300:
    CEYLCNRSTN | EPRCLCPRDM | DLQADGRSCA | RPVVQSCNEL | CEHFCVSNAE | 
    350:
    VPGSYSCMCE | TGYQLAADGH | RCEDVDDCKQ | GPNPCPQLCV | NTKGGFECFC | 
    400:
    YDGYELVDGE | CVELLDPCFG | SNCEFQCQPV | SPTDYRCICA | PGFAPKPDEP | 
    450:
    HKCEMFCNET | SCPADCDPNS | PTVCECPEGF | ILDEGSVCTD | IDECSQGECF | 
    500:
    TSECRNFPGS | YECICGPDTA | LAGQISKDCD | PIPVREDTKE | EEGSGEPPVS | 
    550:
    PTPGSPTGPP | SARPVHSGVL | IGISIASLSL | VVALLALLCH | LRKKQGAARA | 
    577:
    ELEYKCASSA | KEVVLQHVRT | DRTLQKF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse TM
    Cat.:
    E0529m
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse TM
    Cat.:
    E0529d
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse TM
    Cat.:
    E0529b
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    96T
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    ELISA Kit for Mouse TM
    Cat.:
    E0529h
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    96T
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    ELISA Kit for Mouse TM
    Cat.:
    E0529r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse TM
    Cat.:
    U0529b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TM
    Cat.:
    U0529m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TM
    Cat.:
    U0529h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse TM
    Cat.:
    U0529r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TM
    Cat.:
    U0529d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse TM
    Cat.:
    P0529Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse TM
    Polyclonal Antibody for Mouse TM
    Cat.:
    P0529Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse TM
    Polyclonal Antibody for Mouse TM
    Cat.:
    P0529Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse TM
    Monoclonal Antibody for Mouse TM
    Monoclonal Antibody for Mouse TM
    Monoclonal Antibody for Mouse TM
    Monoclonal Antibody for Mouse TM
    Protein for Mouse TM
    Protein for Mouse TM
    Protein for Mouse TM
    Protein for Mouse TM
    Protein for Mouse TM

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Sequence of a cDNA for mouse thrombomodulin and comparison of the predicted mouse and human amino acid sequences."
      Dittman W.A. , Majerus P.W.
      Nucleic Acids Res.17:802-802(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells."
      Dittman W.A. , Kumada T. , Sadler J.E. , Majerus P.W.
      J. Biol. Chem.263:15815-15822(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Czech II.
      tissue: Mammary gland.
    4. 4.
      "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
      Gundry R.L. , Raginski K. , Tarasova Y. , Tchernyshyov I. , Bausch-Fluck D. , Elliott S.T. , Boheler K.R. , Van Eyk J.E. , Wollscheid B.
      Mol. Cell. Proteomics8:2555-2569(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-113
      tissue: Myoblast.
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